BI-GY 7653 Next Generation Sequence Analysis

3 Credits

The online course is aimed at developing practical bioinformatics skills of next generation sequencing analysis.  Students will be introduced to current best practices and in high-throughput sequence data analysis and they will have the opportunity to analyze real data in a high-performance Unix-based computing environment. Special attention will be given to understand the advantages, limitations, and assumptions of most widely bioinformatics methods and the challenges involved in the analysis of large scale datasets. Some of the topics that will be covered include, current sequencing platforms, data formats (FASTA, SAM, BAM, VCF), sequence alignment, sequence assembly, variant calling, RNA-seq analysis, and their biological applications.

 

Prerequisite(s): Students who enroll into this course should have knowledge of Basic of programming, unix tools, and shell scripting.